Driving Directions From the Airport turn right on Fm 1788. Proceed to Hwy 191. /4 miles/ Turn left onto Hwy 191. /9 miles/ At John Ben Sheppard Parkway turn left. Hotel is two blocks down on the right. From I-20 heading west exit 120 which is JBS Parkway. Once on JBS Parkway continue heading north about 3 miles the hotel is located on the left side. From I-20 heading east exit 120 which is JBS Parkway. Once on JBS Parkway continue heading north about 3 miles the hotel is located on the left The Hampton Inn Odessa hotel is located in the Permian Basin of West Texas it is very beautifully decorated with the Texas oil industry in mind and has an atmosphere for the business traveler as well as the corporate and leisure travelers. Beautiful landscaping and a spacious pool area surround us. Located three three blocks from the Music City Mall with a jogging track city park and pond just outside to the west of the hotel the Hampton Inn Odessa is just a few minutes from Midland and within easy reach of shopping dining and other attractions. We love having you here at the Hampton Inn Odessa. Parking side. Located directly across the Street from the University of Texas of the Permian Basin