From San Antonio International Airport - North on Highway 281. West on Highway 1604.North on IH 10 towards El Paso. Exit Highway 87 North San Angelo-Fredericksburg. Turn right onto US 290-East Main Street. From Bergstrom International Airport in Austin - Exit on Presidential Boulevard. Turn left onto Bastrop Highway-TX-71 E. Merge onto TX-71 W. Stay straight to go onto US-290 W. Turn slight right onto US-281N-US-290 W-US-281 S. turn left onto US-290 W/East Main Street. From Kerrville - Take Located on the Main Street in the heart of Fredericksburg Texas this hotel provides ample parking and walking access to the many attractions that make Fredericksburg one of the most popular small towns in the nation. Whether you choose a relaxing stroll downtown a day filled shopping till you drop or a visit to the National Museum of the Pacific War you will find Hampton Inn and Suites Fredericksburg TX the perfect location to start your day. You will have this as well as a variety of dining and leisure entertainment at your finger tips and within walking distance. Fredericksburg has been blending German heritage and Texan hospitality for over 150 years and you*ll find our staff working hard to continue that tradition. Friendly and knowledgeable our staff will make sure that you will experience an enjoyable stay that you will want to repeat again and again. The hotel offers a variety of accommodations and amenities that today*s travelers demand and expect. A romantic get-a-way. The site for your next family reunion. A week-long vacations desitination. A stress-free corporate meeting site. The Hampton Inn and Suites has what you need to make your stay in Fredericksburg the best. Parking TX-16 - turn right onto US-290-US-87-East Main Street. Cross Streets - East Main Street and Lee Street.